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Announcing a New Cohort Exam in The Jackson Heart Study

October 18, 2017

In a recent post on this Digital Forum, NHLBI announced a plan to fund a new examination in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.  NHLBI would now like to announce its intent to fund a new clinical Exam 4 in the Jackson Heart Study (JHS; see NIH Guide Notice NOT-HL-17-542).  Exam 4, which will take place from approximately February 16, 2020 through November 15, 2022, will serve as a platform for additional exam components via investigator-initiated, peer reviewed, independently funded projects to enrich the exam data collection with additional hypothesis-driven content.  The research aims of such exam-related ancillary projects need not be limited to those within the mission of the NHLBI, but must be consistent with and/or complement the JHS’s objectives.  The intent of Notice NOT-HL-17-542 is to allow ample time for interested researchers to comply with JHS requirements and develop NIH grant applications to fund exam components addressing innovative research questions in the JHS.

The Table summarizes timing considerations for submitting grant applications proposing components for the JHS Exam 4.  (See this website for more information about NIH grant application cycles, due dates, etc.)

Potential applicants may wish to consider the following:

  • Receipt of new (A0) applications by the October 2018 Council (Cycle I) and January 2019 Council (Cycle II) standard due dates that receive fundable scores may be awarded with approximately 14 and 10 months, respectively, for planning and preparation before the JHS Exam 4 data collection begins.
  • Receipt of new (A0) applications by the May 2019 Council (Cycle III) standard receipt dates that receive fundable scores may be funded approximately 7 months before the JHS Exam 4 begins. It will have to be determined whether this will be enough time to begin data collection prior to the start of Exam 4.  If not, a start date during the first year of Exam 4 may be possible.
  • For the receipt of new (A0) applications by the October 2018 Council (Cycle I) standard due dates that do not receive fundable scores:
    • Receipt of resubmission (A1) applications by the May 2019 Council (Cycle III) standard due dates receiving fundable scores may be awarded approximately 7 months before the JHS Exam 4 begins.  As noted above, it will have to be determined whether this will be enough time to begin data collection prior to the start of Exam 4.  If not, a start date during the first year of Exam 4 may be possible.
  • Receipt of new (A0) applications by the January 2019 Council (Cycle II) standard due dates that do not receive fundable scores would allow:
    • Receipt of resubmission (A1) applications by the October 2019 Council (Cycle I) standard due dates to enable a funded award approximately 2 months before the JHS Exam 4 begins.  This will not allow adequate time for planning and preparation before Exam 4 begins, but a start date during the first year of the exam may be possible.
  • Receipt of new (A0) applications by the May 2019 Council (Cycle III) standard receipt dates that do not receive fundable scores, receipt of resubmission (A1) applications, will not allow funding until after Exam 4 is underway.

Therefore, for grant applications received after the January 2019 Council (Cycle II) standard due dates (due dates between May 25 and September 7, 2018), applicants will need to consider timing of their data collection relative to that of the planned exam and any additional time and associated costs that may be required to complete their exam components as proposed.

If you are interested in partnering with the JHS in developing and obtaining funding for innovative content for the upcoming exam, please carefully read the NIH Guide Notice (NOT-HL-17-542) and visit the JHS website for its ancillary studies policies and other relevant information.

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