Skip to content

Announcing a New Cohort Exam in The Jackson Heart Study

October 18, 2017

In a recent post on this Digital Forum, NHLBI announced a plan to fund a new examination in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.  NHLBI would now like to announce its intent to fund a new clinical Exam 4 in the Jackson Heart Study (JHS; see NIH Guide Notice NOT-HL-17-542).  Exam 4, which will take place from approximately February 16, 2020 through November 15, 2022, will serve as a platform for additional exam components via investigator-initiated, peer reviewed, independently funded projects to enrich the exam data collection with additional hypothesis-driven content.  The research aims of such exam-related ancillary projects need not be limited to those within the mission of the NHLBI, but must be consistent with and/or complement the JHS’s objectives.  The intent of Notice NOT-HL-17-542 is to allow ample time for interested researchers to comply with JHS requirements and develop NIH grant applications to fund exam components addressing innovative research questions in the JHS.

The Table summarizes timing considerations for submitting grant applications proposing components for the JHS Exam 4.  (See this website for more information about NIH grant application cycles, due dates, etc.)

Potential applicants may wish to consider the following:

  • Receipt of new (A0) applications by the October 2018 Council (Cycle I) and January 2019 Council (Cycle II) standard due dates that receive fundable scores may be awarded with approximately 14 and 10 months, respectively, for planning and preparation before the JHS Exam 4 data collection begins.
  • Receipt of new (A0) applications by the May 2019 Council (Cycle III) standard receipt dates that receive fundable scores may be funded approximately 7 months before the JHS Exam 4 begins. It will have to be determined whether this will be enough time to begin data collection prior to the start of Exam 4.  If not, a start date during the first year of Exam 4 may be possible.
  • For the receipt of new (A0) applications by the October 2018 Council (Cycle I) standard due dates that do not receive fundable scores:
    • Receipt of resubmission (A1) applications by the May 2019 Council (Cycle III) standard due dates receiving fundable scores may be awarded approximately 7 months before the JHS Exam 4 begins.  As noted above, it will have to be determined whether this will be enough time to begin data collection prior to the start of Exam 4.  If not, a start date during the first year of Exam 4 may be possible.
  • Receipt of new (A0) applications by the January 2019 Council (Cycle II) standard due dates that do not receive fundable scores would allow:
    • Receipt of resubmission (A1) applications by the October 2019 Council (Cycle I) standard due dates to enable a funded award approximately 2 months before the JHS Exam 4 begins.  This will not allow adequate time for planning and preparation before Exam 4 begins, but a start date during the first year of the exam may be possible.
  • Receipt of new (A0) applications by the May 2019 Council (Cycle III) standard receipt dates that do not receive fundable scores, receipt of resubmission (A1) applications, will not allow funding until after Exam 4 is underway.

Therefore, for grant applications received after the January 2019 Council (Cycle II) standard due dates (due dates between May 25 and September 7, 2018), applicants will need to consider timing of their data collection relative to that of the planned exam and any additional time and associated costs that may be required to complete their exam components as proposed.

If you are interested in partnering with the JHS in developing and obtaining funding for innovative content for the upcoming exam, please carefully read the NIH Guide Notice (NOT-HL-17-542) and visit the JHS website for its ancillary studies policies and other relevant information.

NHLBI Announces Plan to Fund a Limited CARDIA Year 35 Exam

September 20, 2017

As previously reported on this Digital Forum (https://nhlbiepi.wordpress.com/2014/10/22/recommendations-from-the-nhlbi-working-group-on-epidemiology/), an NHLBI working group comprised of selected members of the NHLBI Advisory Council and Board of External Experts presented a set of seven recommendations for transforming population research to the NHLBI Council in 2014.  The recommendations were subsequently published in 2015 (Roger VL et al. Strategic Transformation of Population Studies: Recommendations of the Working Group on Epidemiology and Population Sciences From the National Heart, Lung, and Blood Advisory Council and Board of External Experts. Am J. Epidemiol 2015;181(6):363-367).  In its Recommendation 7, the working group advised the NHLBI to “implement a competitive peer review–based model for its portfolio of large epidemiologic and population studies,” in which funding decisions for study infrastructure are separated from peer review for innovative research content.

Consistent with that Recommendation 7, the NHLBI recently announced its intent to fund a limited Year 35 clinic exam cycle in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.  (See NIH Guide Notice NOT-HL-17-536; https://grants.nih.gov/grants/guide/notice-files/NOT-HL-17-536.html).  The exam, which will take place from approximately June 1, 2020 through July 31, 2021, will serve as a platform for investigator-initiated, peer-reviewed, independently funded exam components that will enrich the exam data collection with additional hypothesis-driven content. The intent of Notice NOT-HL-17-536; https://grants.nih.gov/grants/guide/notice-files/NOT-HL-17-536.html is to allow ample time for interested researchers to comply with CARDIA requirements and develop NIH grant applications to fund exam components addressing innovative research questions in CARDIA.

Table 1 summarizes timing considerations for submitting grant applications proposing exam components for CARDIA’s Year 35 clinic exam cycle.  (See https://grants.nih.gov/grants/how-to-apply-application-guide/due-dates-and-submission-policies/due-dates.htm for more information about NIH grant application cycles, due dates, etc.)

Potential applicants may wish to consider the following:

  • Resubmission (A1) applications received by the October 2019 Council Cycle (Cycle I) standard due dates would enable an award approximately 6 months before the CARDIA Year 35 clinic exam cycle begins.
  • Receipt of new (A0) applications by the May 2019 Council Cycle (Cycle III) standard receipt dates would allow time for review and potential funding before the Year 35 exam cycle begins but receipt, review, and potential funding of resubmission (A1) applications for the following January 2020 Council Cycle (Cycle II) may not allow adequate preparation time before the exam begins.
  • New (A0) applications received by the October 2019 Council Cycle (Cycle I) standard receipt dates would allow time for review and potential funding but would not allow adequate time for submission, review, and funding of a resubmission (A1) application until after the Year 35 exam is underway.

Therefore, for grant applications received after the October 2019 Council Cycle (Cycle II) standard due dates (due dates between January 25 and May 7, 2019), applicants will need to consider timing of their data collection relative to that of the planned exam and any additional time and associated costs that may be required to complete their exam components as proposed.

If you are interested in partnering with CARDIA in developing and obtaining funding for innovative content for the upcoming exam, please carefully read the NIH Guide Notice (NOT-HL-17-536; https://grants.nih.gov/grants/guide/notice-files/NOT-HL-17-536.html) and visit the CARDIA website (https://www.cardia.dopm.uab.edu/) for its ancillary studies policies and other relevant information.

Epidemiology – HLBS (Heart, Lung, Blood, Sleep), Cancer, and Beyond

August 11, 2015

InNCI-NHLBI Blog Graphic the recent years, the NHLBI and NCI have launched separate discussions about the future of epidemiology. As noted in our previous blog posts, the NHLBI convened a working group that generated its recommendations on the strategic transformation of epidemiology (see published report). The NCI’s own recommendations and proposed actions are outlined in its article, “Transforming Epidemiology for 21st Century Medicine and Public Health.” These recommendations have the potential to benefit the field of epidemiology as a whole, beyond HLBS (heart, lung, blood, and sleep) diseases and cancer.

To facilitate further discussion, we list side by side the recommendations for action that emerged from the NCI and NHLBI processes and group them into 7 common thematic areas: leadership, resources, cohorts, methods, workforce, integration and evaluation (Table 1).

We welcome your input on comments and suggestions for actions to further the implementation of the NCI and NHLBI recommendations, to leverage existing epidemiology resources, and build future ones that enable coverage across multiple diseases. The NCI has concurrently posted this topic on their blog to solicit comments from their epidemiology community as well.

Your Voice Matters

March 30, 2015

announcerThe NHLBI has launched its Strategic Visioning Website to obtain input from all corners of the NHLBI community, including you – the epidemiology researcher. You are asked to identify the most compelling questions and critical challenges to the NHLBI in the coming years. Submissions for this round are due no later than May 15, 2015.

A major recommendation from the NHLBI Working Group on epidemiology stated that the NHLBI should “convene a scientific forum to determine the major scientific questions and methodological needs in epidemiology and population science over the next 10-20 years” (see newly published report and previous NHLBI blog post).  The Strategic Visioning Website allows you to contribute to that forum.

So go ahead and:
• Crystalize your thoughts on the future scientific questions and methods
• Go to the  Strategic Visioning Website
• Submit questions and challenges
• Read and comment on others’ submissions

Contribute to know that your voice from the epidemiology community is heard.

Recommendations from the NHLBI Working Group on Epidemiology

October 22, 2014

000010391045-StarTeamX-small

Ongoing discussions on this Digital Forum since 2012 have focused on ways to creatively transform population science. We previously noted that the NHLBI established a working group consisting of selected members of the  NHLBI Advisory Council and Board of External Experts to consider how to best transform population science. In December of 2013, we posted to this digital forum the working group roster and the charge.

Now, after more than a year of deliberations, the working group has released its draft report and recommendations to the NHLBI Advisory Council for input and consideration.  For your information, the presentation to the NHLBI Council on October 22, 2014 can be found here. 

Dr. Michael Lauer, Director, Division of Cardiovascular Sciences, NHLBI, commented on the Working Group’s recommendations at an NHLBI-hosted webinar on October 24, 2014.  The summary of his remarks can be found here.

We would like to know what you think. Please share your comments about the recommendation with us and the epidemiology community through this Digital Forum.

 

 

 

 

Building Team Science: New Research Opportunities in MESA

February 3, 2014

Goodmesalogo (3)Previous posts described future directions in epidemiology research and opportunities to further team science.  Building on transformative approaches described on this forum (November 1, 2013 and December 20, 2013),  the Multi-Ethnic Study of Atherosclerosis invites interested investigators to develop investigator-initiated grant applications for innovative research that involve new data collection from current study participants. The next MESA contract is anticipated to begin in 2015 and welcomes research that will complement an NHLBI-supported core exam.  If you are interested, contact the MESA investigators now to coordinate the process and scientific components.  Interested investigators should consider the following as they begin this process:

• MESA Ancillary Study Committee will begin reviewing proposals in February in order to meet a June NIH submission deadline. The study has policies, procedures, and timelines for reviewing and approving ancillary study proposals before a grant application may be submitted for funding.

• Please contact the MESA Coordinating Center as soon as possible to ensure that the proposed research is appropriate for the study population, and to ascertain existing data availability and determine resource needs.

• Submission of applications proposing new data collection in study participants should be coordinated so the participant exam components can be conducted in a single participant visit, in order to minimize participant burden and cost.

If you are interested, please visit the study web site via the links provided above, or contact the study directly.

Prepared by the Epidemiology Branch

Towards a Creative Transformation of Epidemiology: Charge for the NHLBI Working Group

December 20, 2013

000010391045-StarTeamX-smallSince the beginning of this Digital Forum in March 2012 we have raised questions and encouraged discussion on how to improve the population based studies of heart, lung, and blood diseases.  As an Institute, we are facing increasing pressures to re-engineer our strategies for supporting “big science” along with Institute-initiated projects.  In a recent post (“Transformation is in the air…”), we noted that the NHLBI would establish a working group on these issues and to consider how best to direct population and clinical epidemiology during this time of big data and small budgets. 

That working group, which includes various members of both the NHLBI Advisory Council and the Board of Extramural Experts, has begun meeting to advise the Institute on the creative transformation of epidemiology.  For your information, the working group roster and the charge are included on this post. If you have any comments, please feel free to share them with us through this Digital Form.